The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Jan. 25, 2022
Inscripta, Inc., Boulder, CO (US);
Phillip Belgrader, Pleasanton, CA (US);
Christian Siltanen, Boulder, CO (US);
William Watterson, Boulder, CO (US);
Burak Dura, Boulder, CO (US);
Bruce Chabansky, Boulder, CO (US);
David Stumbo, Boulder, CO (US);
Eric Smith, Boulder, CO (US);
Jorge Bernate, Boulder, CO (US);
Inscripta, Inc., Boulder, CO (US);
Abstract
This invention relates to compositions of matter, methods, modules and instruments for automated mammalian cell growth and mammalian cell transduction followed by nucleic acid-guided nuclease editing in live mammalian cells. The present compositions and methods entail viral delivery of an editing cassette to live mammalian cells such that the editing cassettes edit the cells and the edited cells continue to grow, preferably using a fully-automated end-to-end instrument to process the cells without human intervention to enhance cell processing uniformity and to maintain the integrity of the cell culture.