The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Sep. 11, 2018
Applicant:
Twist Bioscience Corporation, South San Francisco, CA (US);
Inventor:
Jacob Glanville, San Francisco, CA (US);
Assignee:
Twist Bioscience Corporation, South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/00 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2869 (2013.01); C07K 16/005 (2013.01); C12N 15/1044 (2013.01); C12N 15/1068 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01);
Abstract
Provided herein are methods and compositions relating to G protein-coupled receptor (GPCR) libraries having nucleic acids encoding for a scaffold comprising a GPCR binding domain. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein.