The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Jun. 09, 2020
Applicants:

Mapp Biopharmaceutical, Inc., San Diego, CA (US);

Albert Einstein College of Medicine, Bronx, NY (US);

Adimab, Llc, Lebanon, NH (US);

Inventors:

Zachary A. Bornholdt, Encinitas, CA (US);

Larry Zeitlin, San Diego, CA (US);

Kartik Chandran, Brooklyn, NY (US);

Anna Wec, Lebanon, NH (US);

Laura Walker, Norwich, VT (US);

Assignees:

MAPP BIOPHARMACEUTICAL, INC., San Diego, CA (US);

ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, NY (US);

ADIMAB, LLC, Lebanon, NH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61P 31/14 (2006.01); A61K 39/42 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61P 31/14 (2018.01); A61K 39/42 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6075 (2013.01); A61K 2039/62 (2013.01); C07K 2317/76 (2013.01);
Abstract

Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.


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