The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Oct. 10, 2018
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Gregory Allan Hudalla, II, Gainesville, FL (US);
Margaret Mary Fettis, Gainesville, FL (US);
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Abstract
Described herein are modified gal1 monomers that can contain one or more mutated cysteines and/or can be pegylated. Also described herein are modified gal1 dimers, trimers, and tetramers that can contain one or more modified gal1 monomers as described herein. Also described herein are pharmaceutical formulations containing a modified gal1 monomer, dimer, trimer, and/or tetramer. Also described herein are methods of making the modified gal1 polypeptides and complexes thereof. Also described herein are methods of using the modified gal1 polypeptides and complexes thereof.