The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Aug. 19, 2019
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Rami Hannoush, San Mateo, CA (US);
Harini Kaluarachchi, South San Francisco, CA (US);
Aaron Nile, San Bruno, CA (US);
Cameron Noland, South San Francisco, CA (US);
Yingnan Zhang, Fremont, CA (US);
Lijuan Zhou, Belmont, CA (US);
Xinxin Gao, South San Francisco, CA (US);
Assignee:
Genetech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/415 (2006.01); C07K 14/00 (2006.01); A61K 47/34 (2017.01); A61K 38/16 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); C07K 14/47 (2006.01); C07K 14/81 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/415 (2013.01); A61K 9/0051 (2013.01); A61K 9/5031 (2013.01); A61K 38/00 (2013.01); A61K 38/168 (2013.01); A61K 47/34 (2013.01); C07K 14/001 (2013.01); C07K 14/4702 (2013.01); C07K 14/811 (2013.01); C07K 2319/70 (2013.01);
Abstract
Provided are non-naturally occurring cystine knot peptides (CKPs) that bind to VEGF-A. Additionally, provided are methods of using non-naturally occurring CKPs that bind to VEGF-A, including diagnostic and therapeutic compositions and methods. Non-naturally CKPs that bind low density lipoprotein receptor-related protein 6 (LRP6) are also provided.