The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Apr. 30, 2020
Applicant:

Hookipa Biotech Gmbh, Vienna, AT;

Inventors:

Klaus Orlinger, Vienna, AT;

Thomas Monath, Harvard, MA (US);

Anders Lilja, Vienna, AT;

Sarah Schmidt, Vienna, AT;

Ursula Berka, Baden, AT;

Michael Schwendinger, Neusiedl am See, AT;

Elizabeth Watson, Vienna, AT;

Bettina Kiefmann, Vienna, AT;

Julia Hinteramskogler, St. Poelten, AT;

Gerhard Fuhrmann, Vienna, AT;

Andreas Aspöck, Vienna, AT;

Katherine Cohen, Vienna, AT;

Assignee:

HOOKIPA BIOTECH GMBH, Vienna, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C07K 14/025 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61P 35/00 (2018.01); C07K 14/025 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/20034 (2013.01); C12N 2760/10043 (2013.01); C12N 2760/10051 (2013.01); Y02A 50/30 (2018.01);
Abstract

Provided herein are genetically modified arenaviruses suitable as vaccines against neoplastic diseases or cancer. The invention also relates to pharmaceutical compositions and methods for the prevention or treatment of certain infections causing neoplastic diseases or cancer, such as infections with oncogenic viruses. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of preventing or treating diseases and conditions caused by and associated with infections with Human Papillomavirus (HPV), such as cervical cancer, anogenital cancer, head and neck cancer and skin cancers. Also provided herein are immunotherapies for the treatment of a neoplastic disease, such as a neoplastic disease caused by infection with oncogenic viruses.


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