The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Sep. 26, 2018
Applicants:

Université DE Paris, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Sorbonne Universite, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Etienne Jacotot, Paris, FR;

Elodie Bosc, Brétigny sur Orge, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 207/16 (2006.01); C07D 401/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 207/16 (2013.01); C07D 401/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to a compound of formula (I): wherein P, P, Pand Pare amino acid residues or amino acid like structures. The invention also relates to a compound of formula (I) for its use as a Caspase-2 inhibitor and for its therapeutical use. It also concerns the use of a compound of formula (I) as activity base probe to selectively detect Caspase-2 activity.


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