The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Jul. 24, 2020
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Luke P. Lee, Orinda, CA (US);

Jun Ho Son, Albany, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 7/00 (2006.01); B01L 3/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
B01L 7/52 (2013.01); B01L 3/502707 (2013.01); C12Q 1/686 (2013.01); B01L 2300/0893 (2013.01); B01L 2300/1827 (2013.01); B01L 2300/1861 (2013.01);
Abstract

An LED-driven optical cavity PCR system and method providing fast, accurate and reliable PCR based diagnostics. Thermal cycling for PCR takes place in an optical cavity formed in a microfluidic channel or chamber with thin light absorbing metal films disposed on at least two opposing walls that provide uniform heating between the walls by photothermal light to heat conversion. The opposing metal films may be sized for equal light absorption from a single light source orthogonal to the two opposing films to produce an even temperature elevation between the equally heating films upon a single light exposure. Uniform temperature elevation may also be achieved with films made from two different materials.


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