The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Oct. 19, 2016
Applicant:
Glaxosmithkline Biologicals, S.a., Rixensart, BE;
Inventors:
Christiane Marie-Paule Simone Jeanne Feron, Rixensart, BE;
Stefan Jochen Kemmler, Schlieren, CH;
Michael Thomas Kowarik, Schlieren, CH;
Julien Laurent Quebatte, Schlieren, CH;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/104 (2006.01); A61K 39/385 (2006.01); C07K 14/21 (2006.01); A61K 47/64 (2017.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); C12N 9/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/104 (2013.01); A61K 39/385 (2013.01); A61K 45/06 (2013.01); A61K 47/646 (2017.08); A61K 47/6415 (2017.08); A61P 31/04 (2018.01); C07K 14/21 (2013.01); C12N 9/1014 (2013.01); C12N 9/1051 (2013.01); C12N 9/1081 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/6087 (2013.01); A61K 2039/64 (2013.01); C07K 2319/00 (2013.01); C12Y 201/02002 (2013.01); C12Y 204/01019 (2013.01); C12Y 204/99 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to aPcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of thePcrV carrier protein. The invention also disclosesPcrV proteins that contain glycosylation site consensus sequences.