The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Mar. 16, 2021
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Joshua P. Frederick, Charlestown, MA (US);
Ailin Bai, Newton, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); G06F 3/06 (2006.01); A61K 38/17 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01); G06F 11/30 (2006.01);
U.S. Cl.
CPC ...
G06F 3/0629 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); A61P 35/00 (2018.01); C07K 14/70575 (2013.01); G06F 11/3051 (2013.01); G06F 11/3093 (2013.01);
Abstract
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.