The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
May. 08, 2015
Siemens Healthineers Nederland B.v., The Hague, NL;
Coen Adrianus Verschuren, Eindhoven, NL;
Dominique Maria Bruls, Heeze, NL;
Albert Hendrik Jan Immink, Eindhoven, NL;
Femke Karina De Theije, Berghem, NL;
Thea van der Wijk, Bunnik, NL;
Alexander Marc Van Der Lee, Venlo, NL;
Johannes Joseph Hubertina Barbara Schleipen, Eindhoven, NL;
Siemens Healthineers Nederland B.V., The Hague, NL;
Abstract
The invention relates to a method for the detection of target components that comprise label particles, for example magnetic particles (). The method includes (a) collecting the target components at a binding surface () of a carrier (); (b) directing an input light beam (L, L, L) into the carrier such that it is totally internally reflected in an investigation region () at the binding surface (); and (c) determining the amount of light of an output light beam (L, L, L) that comprises at least some of the totally internally reflected light. Evanescent light generated during the total internal reflection is affected (absorbed, scattered) by target components and/or label particles () at the binding surface () and will therefore be missing in the output light beam (L). This can be used to determine the amount of target components at the binding surface () from the amount of light in the output light beam (L, L, L). A magnetic field generator () is optionally used to generate a magnetic field (B) at the binding surface () by which magnetic label particles () can be manipulated, for example attracted or repelled.