The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Jan. 10, 2019
Celgene Corporation, Summit, NJ (US);
Mary Matyskiela, San Diego, CA (US);
Philip Chamberlain, San Diego, CA (US);
Suzana Sturlini Couto, La Jolla, CA (US);
Katherine Stamp, Montclair, NJ (US);
Philip J. Sherratt, Scotch Plains, NJ (US);
Gang Lu, San Diego, CA (US);
Julia Hui, Basking Ridge, NJ (US);
CELGENE CORPORATION, Summit, NJ (US);
Abstract
A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL; administering the cereblon modifying compound to the sample; determining a second protein level of SALL; comparing the first level and the second protein level of SALLto determine if the cereblon modifying compound induces degradation of SALL; and selecting the cereblon modifying compound that does not induce degradation of SALL