The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

Jan. 17, 2019
Applicant:

Hangzhou Canhelp Genomics Technology Co. Ltd., Hangzhou, CN;

Inventors:

Qinghua Xu, Hangzhou, CN;

Dingwei Ye, Hangzhou, CN;

Qifeng Wang, Hangzhou, CN;

Chengshu Chen, Hangzhou, CN;

Jinying Chen, Hangzhou, CN;

Yifeng Sun, Hangzhou, CN;

Wanli Ren, Hangzhou, CN;

Hongying Wang, Hangzhou, CN;

Yiwang Wu, Hangzhou, CN;

Tao Huo, Hangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/6886 (2018.01); G16B 50/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 50/00 (2019.02); C12Q 2600/158 (2013.01);
Abstract

Disclosed are a set of genes for bladder cancer detection and their use. The set of genes includes the following 32 genes: CA9 gene, CDK1 gene, CTSE gene, DMBT1 gene, ERBB2 gene, HOXA13 gene, IGF2 gene, CXCR2 gene, MAGEA3 gene, MDK gene, MMP1 gene, MMP12 gene, RBP2 gene, CCL18 gene, SNAI2 gene, VEGFA gene, MFAP5 gene, SGK2 gene, WFDC2 gene, POSTN gene, NPFFR2 gene, ANXA10 gene, CTAG2 gene, ZDHHC2 gene, KRT20 gene, PPP1R14D gene, FGD3 gene, AHNAK2 gene, SEMA3D gene, ZNF707 gene, LOC100652931 gene, and LINC00565 gene. After clinical validation, the kit provided by the present invention is used to detect bladder cancer with a high accuracy rate and objective interpretation of results. Meanwhile, as a non-invasive detection, the compliance of patients is greatly improved comparing with the existing cystoscopy, which has an important clinical significance for the early detection and postoperative monitoring of bladder cancer.


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