The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
May. 04, 2018
Applicant:
The United States of America,as Represented BY the Secretary,department of Health and Human Services, Bethesda, MD (US);
Inventors:
Giovanna Tosato, Bethesda, MD (US);
Hidetaka Ohnuki, Rockville, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/14 (2006.01); C12Q 1/6834 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6874 (2018.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/6834 (2013.01); C12N 1/14 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6874 (2013.01); B82Y 5/00 (2013.01); C07K 2317/77 (2013.01); C12Q 2523/101 (2013.01); C12Q 2565/518 (2013.01); C12Q 2565/629 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Methods and kits for preparing re-usable single cells are described. Cell components are anchored using a nano-scale scaffold to create a re-usable single cell. The nano-scale scaffold may be a polyacrylamide nano-scale scaffold. Methods to determine modifications of the genome, transcriptome, or epigenome are described.