The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

May. 18, 2018
Applicants:

Ecole Polytechnique, Palaiseau, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Thierry Gacoin, Bures-sur-Yvette, FR;

Maximilian Richly, Paris, FR;

Pascal Preira, Savigny-sur-Orge, FR;

Antigoni Alexandrou, Palaiseau, FR;

Cédric Bouzigues, Paris, FR;

Rabei Mohammedi, Gif-sur-Yvette, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09K 11/02 (2006.01); C09K 11/77 (2006.01); G01N 33/543 (2006.01); A61K 33/02 (2006.01); A61K 49/10 (2006.01); C01F 1/00 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C09K 11/025 (2013.01); A61K 33/02 (2013.01); A61K 49/0065 (2013.01); A61K 49/101 (2013.01); C01F 1/00 (2013.01); C09K 11/7794 (2013.01); G01N 33/54346 (2013.01); C01P 2006/40 (2013.01); G01N 2458/40 (2013.01);
Abstract

The present invention concerns a luminescent particle comprising a nanoparticle of formulaALnVO(PO)  (I)in which A is selected from yttrium (Y), gadolinium (Gd), lanthanum (La), and mixtures thereof; Ln is selected from europium (Eu), dysprosium (Dy), samarium (Sm), neodymium (Nd), erbium (Er), ytterbium (Yb), and mixtures thereof; 0<x<1; and 0≤y<1; characterized in that the nanoparticle on its surface has tetraalkylammonium cations in an amount such that said nanoparticle has a zeta potential, ζ, of less than or equal to −28 mV in an aqueous medium with a pH≥5, more particularly with a pH≥5.5, and with an ionic conductivity >100 μS·cm. It also concerns a method for preparing such luminescent particles, a colloidal suspension of these particles, and the use thereof as a diagnostic agent, and also a diagnostic kit comprising such luminescent particles.


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