The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

Oct. 22, 2018
Applicant:

Laboratory Corporation of America Holdings, Burlington, NC (US);

Inventors:

Weidong Huang, Pleasanton, CA (US);

Jodi Weidler, Foster City, CA (US);

Jeff Sperinde, El Granada, CA (US);

Mojgan Haddad, Orinda, CA (US);

Michael Bates, San Carlos, CA (US);

John William Winslow, El Granada, CA (US);

Xueguang Jin, Fremont, CA (US);

Gerald J. Wallweber, Foster City, CA (US);

Jennifer W. Cook, San Mateo, CA (US);

Gundo Diedrich, South San Francisco, CA (US);

Laurie Goodman, El Granada, CA (US);

Ali Mukherjee, Millbrae, CA (US);

Gordon Parry, Oakland, CA (US);

Stephen J. Williams, San Carlos, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/32 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01); A61P 35/00 (2006.01); G01N 33/74 (2006.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12Q 1/6886 (2013.01); G01N 33/5005 (2013.01); G01N 33/57407 (2013.01); G01N 33/57415 (2013.01); G01N 33/57484 (2013.01); G01N 33/6893 (2013.01); G01N 33/74 (2013.01); A61K 2039/505 (2013.01); C07K 2317/30 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/71 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.


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