The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Nov. 17, 2017
Applicant:
Seattle Genetics, Inc., Bothell, WA (US);
Inventors:
David A. Eavarone, North Quincy, MA (US);
Jeffrey Behrens, Newton, MA (US);
Alexey Alexandrovich Lugovskoy, Woburn, MA (US);
Assignee:
Seagen Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61P 35/04 (2018.01); C07K 16/46 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01);
Abstract
The present disclosure provides antibodies with T cell-interacting regions and/or glycan-interacting regions. Bispecific antibodies capable of recruiting T cells to cancer cells are also provided, including bispecific antibodies capable of recruiting T cells to cancer cells expressing sialyl Tn (STn). The present disclosure also includes methods for killing cells by targeting them with antibodies having T cell-interacting regions.