The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Jul. 23, 2018
Applicant:
Novimmune SA, Geneva, CH;
Inventors:
Assignee:
NovImmune SA, Geneva, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07K 16/06 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); A61P 35/00 (2018.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); C07K 16/2803 (2013.01); C07K 16/30 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01);
Abstract
The invention relates to the generation of multispecific antibody mixtures include a subset of antibodies isolated from a mixture of two or more monospecific antibodies and one or more bispecific antibodies, wherein all antibodies in the subset have the same common heavy chain. The invention also relates to methods of isolating, purifying, or otherwise producing such a subset of antibodies by using at least one affinity chromatography step. The invention also relates to methods of using such a subset of antibodies in a variety of therapeutic indications.