The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

Oct. 19, 2018
Applicant:

Kala Pharmaceuticals, Inc., Watertown, MA (US);

Inventors:

Pawel Wojciech Nowak, Woodcliff, NJ (US);

Winston Z. Ong, Stoneham, MA (US);

Assignee:

Kala Pharmaceuticals, Inc., Arlington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/517 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 9/0048 (2013.01); C07B 2200/05 (2013.01);
Abstract

Provided herein are compounds, compositions, and pharmaceutical compositions of Formula (I). Also provided herein are methods of using compounds of Formula (I) to treat proliferative diseases, ocular diseases, dermatological diseases, inflammatory diseases, autoimmune diseases, autoinflammatory diseases, and metabolic diseases. Also provided herein are methods of using the compounds of Formula (I) as therapeutics, e.g., in the treatment and/or prevention of diseases associated with growth factor activity or angiogenesis. In some embodiments, the disease being treated is a proliferative disease.


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