The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Aug. 06, 2020
Novartis Ag, Basel, CH;
Christine Hiu-Tung Chen, Waltham, MA (US);
Zhuoliang Chen, Belmont, MA (US);
Jorge Garcia Fortanet, Wilmington, MA (US);
Denise Grunenfelder, Pasadena, CA (US);
Rajesh Karki, Quincy, MA (US);
Mitsunori Kato, Long Island, NY (US);
Matthew J. LaMarche, Reading, MA (US);
Lawrence Blas Perez, Silver Springs, MD (US);
Travis Matthew Stams, Stow, MA (US);
Sarah Williams, Emeryville, CA (US);
NOVARTIS AG, Basel, CH;
Abstract
The present invention relates to compounds of formula I: in which m, Y, Y, Y, R, R, R, R, R, R, R, Rand Rare defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.