The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

Jun. 19, 2020
Applicant:

National Cheng Kung University, Tainan, TW;

Inventors:

Chen-Sheng Yeh, Tainan, TW;

Liu-Chun Wang, Tainan, TW;

Zheng-Zhe Chen, Kaohsiung, TW;

Ping-Ching Wu, Tainan, TW;

Chia-Hao Su, Kaohsiung, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 65/03 (2006.01); C07F 3/00 (2006.01); C07F 7/00 (2006.01); A61K 49/00 (2006.01); C07F 7/18 (2006.01); C07F 3/06 (2006.01); C09K 11/06 (2006.01); A61K 49/04 (2006.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
C07C 65/03 (2013.01); A61K 49/0428 (2013.01); C07F 3/06 (2013.01); C07F 7/1804 (2013.01); C09K 11/06 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C09K 2211/188 (2013.01);
Abstract

Disclosed herein are modified chromium-dpoed zinc gallate (ZGC) nanocubes, which are characterized in respectively having a concave surface that is modified with (3-aminopropyl)triethoxysilane (APTES). The modified ZGC nanocubes produce long lasting luminescence (LLL) that lasts for at least 1.5 hours under X-ray or UV excitation. Also disclosed herein are methods for the preparation of the modified ZGC nanocubes; and methods for imaging an area of interest (e.g., cancer) in a live subject using the modified ZGC nanocubes as an imaging agent.


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