The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Apr. 11, 2018
Applicant:
Seattle Children's Hospital, Seattle, WA (US);
Inventors:
Andrew M. Scharenberg, Seattle, WA (US);
Kyle Jacoby, Seattle, WA (US);
Alexandra E. Grier, Seattle, WA (US);
Assignee:
SEATTLE CHILDREN'S HOSPITAL, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/63 (2006.01); C12N 15/67 (2006.01); C12P 19/34 (2006.01); A61K 41/00 (2020.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A61K 41/0047 (2013.01); C12N 15/63 (2013.01); C12N 15/67 (2013.01); C12P 19/34 (2013.01); C12N 2710/10343 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Disclosed herein are polynucleotides having a plurality of thymine nucleotides and an endonuclease recognition site inserted therein, methods of engineering the polynucleotides having a plurality of thymine nucleotides and an endonuclease recognition site inserted therein, and methods of enhancing transcription, translation, and increasing stability of a polynucleotide.