The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
May. 19, 2017
Applicant:
Biohaven Pharmaceutical Holding Company Ltd., New Haven, CT (US);
Inventor:
Vladimir Coric, Madison, CT (US);
Assignee:
Biohaven Therapeutics Ltd., New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/428 (2006.01); C07K 16/28 (2006.01); A61K 31/426 (2006.01); A61K 45/06 (2006.01); C07D 277/82 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/426 (2013.01); A61K 31/428 (2013.01); A61K 39/39566 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 277/82 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract
Disclosed are methods of treating cancer using a combination of an immunotherapeutic agent, such as, for example, a PD-1, PD-L1 or CTLA-4 checkpoint inhibitor, and a glutamate modulating agent such as riluzole or trigriluzole. Pharmaceutical compositions including the immunotherapeutic agents and glutamate modulating agents are also disclosed.