The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2022

Filed:

Mar. 14, 2017
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

University of North Carolina Chapel Hill, Chapel Hill, NC (US);

Inventors:

Roberta Polak, Boston, MA (US);

Robert E. Cohen, Jamaica Plain, MA (US);

Michael F. Rubner, Westford, MA (US);

Elena V. Batrakova, Chapel Hill, NC (US);

Matthew J. Haney, Chapel Hill, NC (US);

Natalia L. Klyachko, Moscow, RU;

Yuling Zhao, Chapel Hill, NC (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 35/15 (2015.01); A61K 38/44 (2006.01); A61K 47/69 (2017.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 35/28 (2013.01); A61K 38/44 (2013.01); A61K 47/6815 (2017.08); A61K 47/6835 (2017.08); A61K 47/6901 (2017.08); C12Y 111/01006 (2013.01);
Abstract

Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).


Find Patent Forward Citations

Loading…