The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
May. 16, 2018
The University of Sheffield, Sheffield, GB;
Gareth Richards, Sheffield, GB;
Timothy M. Skerry, Sheffield, GB;
Joseph P. A. Harrity, Sheffield, GB;
Jean-Olivier Zirimwabagabo, Sheffield, GB;
Matthew J. Tozer, Sheffield, GB;
Karl Richard Gibson, Sandwich, GB;
Roderick Alan Porter, Sheffield, GB;
Paul Matthew Blaney, Chapel-en-le-Frith, GB;
Paul Alan Glossop, Sandwich, GB;
The University of Sheffield, Sheffield, GB;
Abstract
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein R, R, R, R, R, R, R, R, X, X, X, X, Land n are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM). Also disclosed are the compounds for use in the treatment of diseases modulated AM, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.