The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2022

Filed:

Jul. 10, 2018
Applicants:

Pebble Labs Inc., Los Alamos, NM (US);

Colorado State University Research Foundation, Fort Collins, CO (US);

Inventors:

Richard Sayre, Los Alamos, NM (US);

Jiannong Xu, Las Cruces, NM (US);

Bradley R. Borlee, Fort Collins, CO (US);

Konstantinos Lymperopoulos, Los Alamos, NM (US);

Rebekah Kading, Fort Collins, CO (US);

William Black, Fort Collins, CO (US);

Kenneth Olson, Fort Collins, CO (US);

Carol Blair, Fort Collins, CO (US);

Assignees:

PEBBLE LABS INC., Los Alamos, NM (US);

COLORADO STATE UNIVERSITY RESEARCH FOUNDATION, Fort Collins, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A01N 25/00 (2006.01); A01N 57/16 (2006.01); A01N 63/00 (2020.01); A01N 63/14 (2020.01); C12N 1/20 (2006.01); A01N 63/60 (2020.01);
U.S. Cl.
CPC ...
C12N 15/1131 (2013.01); A01N 25/006 (2013.01); A01N 57/16 (2013.01); A01N 63/60 (2020.01); C12N 1/20 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2330/51 (2013.01);
Abstract

The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel paratransgenic system configured to deliver one or more inhibitory RNA molecules to pathogen/disease-transmitting organisms. In a preferred embodiment, the invention may include one or more genetically engineered symbiotic bacteria configured to persist throughout the life-cycle of a mosquito and deliver one or more interfering RNA molecules to pathogen/disease-transmitting mosquitoes.


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