The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2022
Filed:
Jul. 22, 2021
Genmab Holding B.v., Utrecht, NL;
Simone Oostindie, Utrecht, NL;
Frank Beurskens, Utrecht, NL;
Esther Breij, Utrecht, NL;
Edward Van Den Brink, Utrecht, NL;
Andreas Hollenstein, Utrecht, NL;
Marije Overdijk, Utrecht, NL;
Margaret Lindorfer, Keswick, VA (US);
Ronald Taylor, Keswick, VA (US);
Paul Parren, Odijk, NL;
Hilma Van Der Horst, Utrecht, NL;
Martine E. D. Chamuleau, Amsterdam, NL;
Tuna Mutis, Amsterdam, NL;
GENMAB HOLDING B.V., Utrecht, NL;
Abstract
CD37-specific bispecific antibody molecules binding to different epitopes of the human CD37 antigen which bispecific antibody molecules have enhanced Fc-Fc interactions upon binding to CD37 on the cell surface. The invention also relates to the monoclonal parental antibodies from which the first or the second binding region of the bispecific antibody molecules is obtained. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of cancer and other diseases using these compositions.