The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2022
Filed:
Jun. 15, 2018
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Randall T. Peterson, Salt Lake City, UT (US);
Aarti Asnani, Arlington, MA (US);
Yan Liu, Boston, MA (US);
Baohui Zheng, Boston, MA (US);
You Wang, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/04 (2006.01); A61P 35/04 (2006.01); A61K 31/704 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 493/04 (2013.01); A61K 31/704 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01);
Abstract
The present application provides tricyclic compounds useful, e.g., in treating or preventing cardiotoxicity and cardiomyopathy in patients undergoing cardiotoxic chemotherapy. Methods of making and using the tricyclic compounds to treat cancer are also described.