The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2022

Filed:

May. 02, 2019
Applicant:

New Mexico Tech University Research Park Corporation, Socorro, NM (US);

Inventors:

Rodolfo Tello-Aburto, Albuquerque, NM (US);

Snezna Rogelj, Socorro, NM (US);

Liam Hallada, Albuquerque, NM (US);

Doleshwar Niroula, Socorro, NM (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 305/12 (2006.01);
U.S. Cl.
CPC ...
C07D 305/12 (2013.01);
Abstract

The disclosure provides proteasome inhibitors that can be used to halt cell division of rapidly dividing cells by preventing the degradation of cell cycle-regulating proteins, such as cyclins, cyclin-dependent kinase inhibitors, and p53. The proteasome inhibitor compounds can be used to inhibit the proliferation of cancer cells.


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