The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2022

Filed:

Apr. 02, 2019
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Terry Moore, Chicago, IL (US);

Phillip Lazzara, Chicago, IL (US);

Brian David, Chicago, IL (US);

Benjamin Richardson, West Palm Beach, FL (US);

Atul D. Jain, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/22 (2006.01);
U.S. Cl.
CPC ...
C07D 217/22 (2013.01);
Abstract

Disclosed herein are compounds that can act as inhibitors of the Kelch-like ECH-associated protein 1/nuclear factor (erythroid-derived 2)-like 2 ('KEAP1/NRF2') protein-protein interaction, and methods of using the compounds to treat and prevent diseases and disorders, such as COPD, multiple sclerosis, and diabetes, and in the promotion of wound healing. The compounds described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: formula (I), wherein the substituents are as described.


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