The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Feb. 09, 2016
Applicant:

B.r.a.h.m.s Gmbh, Hennigsdorf, DE;

Inventors:

Maryann Stephanie Vogelsang, Natick, MA (US);

Bryan Krastins, Whitingham, VT (US);

Anne Incamps, Saint Victor la Coste, FR;

Andre Schoenichen, Berlin, DE;

Tim Ziera, Berlin, DE;

Assignee:

B.R.A.H.M.S. GMBH, Henningsdorf, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6875 (2013.01); G01N 33/6848 (2013.01); G01N 33/6893 (2013.01); G01N 2800/24 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to method for detecting a free histone protein in a biological sample of a subject, e.g. using an immunoassay or a mass spectrometric assay. It also pertains to a method for the diagnosis, prognosis, risk assessment, risk stratification and/or therapy control of a disease or medical condition, comprising detecting a free histone protein or peptide fragment thereof in a biological sample of a subject, wherein the presence of said free histone protein or fragment thereof is indicative for said disease or medical condition.


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