The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Mar. 31, 2020
Applicants:

Editas Medicine, Inc., Cambridge, MA (US);

The Broad Institute, Inc., Cambridge, MA (US);

The University of Iowa Research Foundation, Iowa City, IA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Feng Zhang, Cambridge, MA (US);

Deborah Palestrant, Newton, MA (US);

Beverly Davidson, Iowa City, IA (US);

Jordi Mata-Fink, Somerville, MA (US);

Edgardo Rodriguez, Gainesville, FL (US);

Alexis Borisy, Boston, MA (US);

Assignees:

Editas Medicine, Inc., Cambridge, MA (US);

The Broad Institute Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

University of Iowa Research Foundation, Iowa City, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/90 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/902 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/111 (2013.01); C12N 15/1137 (2013.01); C12N 15/63 (2013.01); C12N 2310/10 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex.


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