The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Mar. 11, 2020
Applicant:
Varigen Biosciences Corporation, Middleton, WI (US);
Inventors:
Robert Joseph Stankey, Madison, WI (US);
David Mead, Middleton, WI (US);
Assignee:
VARIGEN BIOSCIENCES CORPORATION, Middleton, WI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 15/86 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01);
Abstract
Disclosed herein are recombinant methods of activating expression of one or more biosynthetic gene clusters comprising more than one gene, the method comprising a recombinant DNA expression vector that possess two opposable inducible promoters that drives expression of a biosynthetic gene cluster exogenously from outside of the cluster to produce polyketides or non-ribosomal peptides in a heterologous host.