The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Jun. 28, 2018
Applicants:

Illumina, Inc., San Diego, CA (US);

Illumina Cambridge Limited, Cambridge, GB;

Inventors:

Brian D. Mather, San Diego, CA (US);

Cyril Delattre, San Diego, CA (US);

Tarun Kumar Khurana, Freemont, CA (US);

Yir-Shyuan Wu, Albany, CA (US);

Pallavi Daggumati, San Francisco, CA (US);

Behnam Javanmardi, Saratoga, CA (US);

Filiz Gorpe-Yasar, Redwood City, CA (US);

Sebastien Georg Gabriel Ricoult, Cambridge, GB;

Xavier von Hatten, Cambridge, GB;

Daniel Leonard Fuller, Sudbury, GB;

Assignees:

Illumina, Inc., San Diego, CA (US);

Illumina Cambridge Limited, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12N 15/10 (2006.01); C08F 226/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1017 (2013.01); C08F 226/10 (2013.01); C12N 15/1006 (2013.01); C12N 15/1013 (2013.01);
Abstract

In the examples set forth herein, nucleic acid extraction materials are capable of selectively extracting cell free nucleic acids, including cell free DNA, directly from whole blood samples or plasma. Also included are methods of making and using the nucleic acid extraction materials. One example of a nucleic acid extraction material includes a substrate. This example of the nucleic acid extraction material also includes a polycation bonded to at least a portion of a surface of the substrate. In this example, the polycation consists of a polymer of a quaternized monomer selected from the group consisting of a quaternized 1-vinylimidazole monomer and a quaternized dimethylaminoethyl methacrylate monomer, or a copolymer of a neutral monomer and the quaternized monomer.


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