The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Apr. 26, 2019
Applicants:

Editas Medicine, Inc., Cambridge, MA (US);

Duke University, Durham, NC (US);

Inventors:

Ari E. Friedland, Boston, MA (US);

Penrose O'Donnell, Yarmouth, MA (US);

David A. Bumcrot, Belmont, MA (US);

Bryan R. Cullen, Durham, NC (US);

Assignees:

EDITAS MEDICINE, INC., Cambridge, MA (US);

DUKE UNIVERSITY, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/1133 (2013.01); C12N 2310/20 (2017.05);
Abstract

Genome editing systems and genetic constructs that target a herpes simplex virus (HSV) viral gene, where the systems comprise one Cas9 molecule, and a gRNA molecule, compositions and cells comprising such genome editing systems and genetic constructs as well as methods for using the genome editing systems, genetic constructs, compositions and cells for genome engineering, and for preventing, treating or reducing HSV infection.


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