The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Nov. 29, 2017
Applicants:

Fondazione Ri.med, Palermo, IT;

Istituto Mediterraneo Per I Trapianti E Terapie Ad Alta Specializzazione . Ismett, Palermo, IT;

Inventor:

Ester Badami, Palermo, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 35/17 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 2501/2302 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/24 (2013.01);
Abstract

The present invention refers to a method for the production of activated CD3-CD56+ NK cells, activated CD3-CD56 NK+ cells obtainable with the method, their use, in particular for the treatment of a tumor, preferably a hepatocellular carcinoma (HCC), for use in the treatment and/or prevention of an HCV infection, for use in the treatment and/or prevention of a post-liver transplant HCV reinfection, or for use for prevention of a post-liver transplant HCC recurrence. The invention also concerns pharmaceutical compositions including the activated CD3-CD56+ NK cells.


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