The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Dec. 31, 2015
Applicant:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Inventors:
Stephen R. Comeau, Avon, NY (US);
Andrew Nixon, Hanover, MA (US);
Niksa Kastrapeli, Wellesley, MA (US);
Jon A. Kenniston, Hingham, MA (US);
Gregory P. Conley, Arlington, MA (US);
Shauna Mason, Arlington, MA (US);
Allison P. Lindberg, Arlington, MA (US);
Kristopher Kopacz, Cumberland, RI (US);
Burt Adelman, Concord, MA (US);
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C12N 15/13 (2006.01); C07K 16/36 (2006.01); A61P 7/02 (2006.01); A61K 39/395 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/395 (2013.01); A61P 7/02 (2018.01); C07K 16/36 (2013.01); C12N 9/64 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01); C07K 2317/94 (2013.01);
Abstract
Described herein are bispecific antibodies that bind to plasma kallikrein (pKal) and Factor XII and methods of producing and using such bi-specific antibodies for treating diseases or disorders associated with the contact system, e.g., hereditary angioedema or thrombosis.