The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Aug. 09, 2018
Applicant:
University of Saskatchewan, Saskatoon, CA;
Inventors:
Bharathikumar Vellalore Maruthachalam, Saskatoon, CA;
Ayman Elsayed Mohammad, Saskatoon, CA;
Jianghai Liu, Saskatoon, CA;
Humphrey Fonge, Saskatoon, CA;
Kris Barreto, Saskatoon, CA;
Clarence Ronald Geyer, Saskatoon, CA;
Assignee:
University of Saskatchewan, Saskatoon, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); G01N 33/573 (2006.01); C07K 16/32 (2006.01); A61K 47/64 (2017.01); A61K 9/00 (2006.01); A61K 49/00 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 9/0019 (2013.01); A61K 47/6415 (2017.08); A61K 49/0058 (2013.01); G01N 33/574 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/92 (2013.01); G01N 2333/705 (2013.01);
Abstract
The disclosure is directed to antibodies and binding fragments thereof that specifically bind HER3. The disclosure is further directed to immunoconjugates comprising the antibodies and binding fragments thereof that specifically bind HER3. The disclosure is also directed to uses of the antibodies, binding fragments thereof and immunoconjugates for detecting HER3-expressing cells and for treating HER3-expressing cancer.