The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
May. 18, 2020
Applicants:
The Regents of the University of Colorado, Denver, CO (US);
The Regents of the University of California, Oakland, CA (US);
Inventors:
Jeffery L. Bennett, Aurora, CO (US);
Gregory P. Owens, Aurora, CO (US);
Alan S. Verkman, San Francisco, CA (US);
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
THE REGENTS OF THE UNIVERSITY OF COLORAD, Denver, CO (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/28 (2013.01); C07K 2317/21 (2013.01); C07K 2317/71 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis.