The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Dec. 11, 2017
Applicants:
Astellas Pharma Inc., Tokyo, JP;
National Center for Global Health and Medicine, Tokyo, JP;
Hiroshima University, Higashihiroshima, JP;
Inventors:
Hideki Endo, Tokyo, JP;
Yukihito Ishizaka, Tokyo, JP;
Takashi Yamamoto, Hiroshima, JP;
Tetsushi Sakuma, Hiroshima, JP;
Assignees:
Astellas Pharma Inc., Tokyo, JP;
National Center for Global Health and Medicine, Tokyo, JP;
Hiroshima University, Hiroshima, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/195 (2006.01); C12N 5/0735 (2010.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01); C12N 9/50 (2006.01); C12N 15/113 (2010.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/195 (2013.01); C07K 14/00 (2013.01); C12N 5/0606 (2013.01); C12N 5/0656 (2013.01); C12N 5/0662 (2013.01); C12N 9/506 (2013.01); C12N 15/113 (2013.01); C12Y 304/22044 (2013.01); C07K 2319/00 (2013.01); C12N 2310/20 (2017.05); C12N 2501/998 (2013.01); C12Y 301/00 (2013.01); C12Y 301/21004 (2013.01);
Abstract
It is intended to provide a fusion polypeptide that regulates the transcription of a target gene. The present inventors have provided a fusion polypeptide comprising: a cell-penetrating peptide; a DNA-binding polypeptide; and a transcriptional regulator.