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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11390646 B1

PDFFull Text
Date of Patent:
Jul. 19, 2022

Filed:

May. 26, 2020

Structure-based peptide inhibitors of α-synuclein aggregation

Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

David S. Eisenberg, Los Angeles, CA (US);

Smriti Sangwan, Los Angeles, CA (US);

Lin Jiang, Santa Monica, CA (US);

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorney:

Gates & Cooper LLP

Primary Examiner:

Adam Weidner

Int. Cl.
CPC ...
C07K 7/02 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); C07K 7/08 (2006.01); A61P 25/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/02 (2013.01); A61P 25/16 (2018.01); C07K 7/08 (2013.01); C07K 14/47 (2013.01); C07K 14/4711 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); C07K 2319/10 (2013.01); G01N 2800/2835 (2013.01);
Abstract

This invention relates to inhibitory peptides which bind to α-synuclein molecules and inhibit α-synuclein amyloidogenic aggregation, α-synuclein cytotoxicity, and spread of α-synuclein. Methods of making and using the inhibitory peptides (e.g. to treat subjects having conditions or diseases that are mediated by α-synuclein, such as Parkinson's disease, dementia with Lewy bodies, or MSA) are described.

Find Patent Forward Citations

Eisenberg, David. (2022). Structure-based peptide inhibitors of α-synuclein aggregation (U.S. Patent No. 11390646). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11390646

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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