The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Feb. 26, 2020
Applicant:

Aluda Pharmaceuticals, Inc., Menlo Park, CA (US);

Inventors:

Qizheng Yao, Jiangsu, CN;

Jianping Wu, Anhui, CN;

Ruihuan Chen, Union City, CA (US);

Lei Zhang, Jiangsu, CN;

Shining Yao, Jiangsu, CN;

Lian Mo, Union City, CA (US);

Qingqing Zhang, Jiangsu, CN;

Assignee:

Aluda Pharmaceuticals, Inc., Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 251/48 (2006.01); C07D 403/04 (2006.01); C07D 251/16 (2006.01); C07D 251/18 (2006.01); A61P 35/00 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 251/48 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); C07D 251/16 (2013.01); C07D 251/18 (2013.01); C07D 403/04 (2013.01);
Abstract

The present invention provides a 2,4,6-trisubstituted s-triazine compound represented by general formula (I) or pharmaceutically acceptable salts, prodrugs or solvates thereof, a preparation method therefor, and use of these compounds in preparing drugs for preventing or treating diseases associated with protein kinase and vimentin dysregulation, and cell vacuolization, and in particular, drugs for treating or preventing cancer growth and metastasis, tissue fibrosis and atherosclerosis.


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