The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Aug. 16, 2017
Applicant:

Imago Biosciences, Inc., San Carlos, CA (US);

Inventors:

Amy E. Tapper, Boston, MA (US);

Cassandra Celatka, Hull, MA (US);

Arthur Glenn Romero, Chesterfield, MO (US);

John M. McCall, Boca Grande, FL (US);

Toni Chancellor, San Carlos, CA (US);

Jian-Xie Chen, Schenectady, NY (US);

Xuemei Chen, Voorheesville, NY (US);

He Zhao, Madison, CT (US);

Betina Biolatto, Manalapan, NJ (US);

Elisabeth C. A. Brot, Albany, NY (US);

Zhihua Li, Beijing, CN;

Xiaoming Liao, Beijing, CN;

Assignee:

Imago Biosciences, Inc., San Carlos, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/06 (2006.01); B01J 21/18 (2006.01); B01J 23/44 (2006.01);
U.S. Cl.
CPC ...
C07D 249/06 (2013.01); B01J 21/18 (2013.01); B01J 23/44 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.


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