The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Jan. 19, 2017
Applicants:

Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;

Tel Hashomer Medical Research Infrastructure and Services Ltd., Ramat Gan, IL;

Inventors:

Talia Shekhter Zehavi, Petah-Tikva, IL;

Ehud Gazit, Ramat-Hasharon, IL;

Mor Herman-Oron, Ramat Efal Ramat Gan, IL;

Genady Kostenich, Ramat Gan, IL;

Arie Orenstein, Tel Aviv, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 47/60 (2017.01); A61K 38/31 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A61K 38/31 (2013.01); A61K 47/60 (2017.08); A61K 47/64 (2017.08); A61P 35/00 (2018.01);
Abstract

The present invention provides nanoparticle conjugates incorporating the self-assembling module diphenylalanine (FF) dipeptide into a bioactive moiety. The conjugate self-assembles to form distinct nanometric structures such as nanospheres. The present invention further provides nanoparticles formed by supramolecular co-assembly of the conjugates with a diphenylalanine (FF) dipeptide or analog thereof, to generate bioactive self-assembled nanostructures.


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