The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Sep. 04, 2018
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Richard J. Porambo, Norristown, PA (US);

Chitrananda Abeygunawardana, Ambler, PA (US);

Luwy Kavuka Musey, Blue Bell, PA (US);

Michael J. Kosinski, Souderton, PA (US);

Yadong Adam Cui, Norristown, PA (US);

Inventors:

Richard J. Porambo, Norristown, PA (US);

Chitrananda Abeygunawardana, Ambler, PA (US);

Luwy Kavuka Musey, Blue Bell, PA (US);

Michael J. Kosinski, Souderton, PA (US);

Yadong Adam Cui, Norristown, PA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/61 (2017.01); A61K 47/64 (2017.01); A61P 37/04 (2006.01); A61K 39/09 (2006.01); A61K 39/39 (2006.01); A61K 47/02 (2006.01); A61K 47/22 (2006.01); C08B 37/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/61 (2017.08); A61K 39/092 (2013.01); A61K 39/39 (2013.01); A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61K 47/646 (2017.08); A61K 47/6415 (2017.08); A61P 37/04 (2018.01); C08B 37/006 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/70 (2013.01);
Abstract

The present invention provides capsular polysaccharides fromserotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additionalserotypes.


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