The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Nov. 15, 2018
Applicant:

University of Washington, Seattle, WA (US);

Inventors:

Edward A. Clark, Seattle, WA (US);

Che-Leung Law, Seattle, WA (US);

Deborah Fuller, Seattle, WA (US);

Michael Gale, Seattle, WA (US);

Assignees:

University of Washington, Seattle, WA (US);

Abacus Bioscience, Inc., Sammamish, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); A61P 31/20 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/292 (2013.01); A61P 31/20 (2018.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); A61K 2039/6056 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01);
Abstract

Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpreS1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof.


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