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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11389526 B1

PDFFull Text
Date of Patent:
Jul. 19, 2022

Filed:

Apr. 18, 2019

Self-attenuated prophylactic and therapeutic vaccines against pathogens

Applicant:

Texas Tech University System, Lubbock, TX (US);

Inventors:

Mingtao Zeng, El Paso, TX (US);

Ke Wen, Harrison, NY (US);

Assignee:

Texas Tech University System, Lubbock, TX (US);

Attorneys:

Edwin S. Flores

Daniel J. Chalker

Chalker Flores, LLP

Primary Examiner:

Bao Q Li

Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61K 39/39 (2006.01); C12N 15/113 (2010.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); C12N 15/1131 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/53 (2013.01); C12N 2310/141 (2013.01); C12N 2760/16134 (2013.01);
Abstract

The present invention includes a live, self-attenuated therapeutic vaccine, virus and methods of making and using the same, comprising: an isolated virus comprising a viral genome that expresses one or more viral antigens; and an artificial microRNA 30 (amiR-30) expression cassette inserted into a viral neuraminidase (NA) or a viral non-structural (NS) gene segment that expresses an amiR-30 that specifically inhibits the expression of a host gene essential for influenza virus replication in host cells.

Find Patent Forward Citations

Zeng, Mingtao. (2022). Self-attenuated prophylactic and therapeutic vaccines against pathogens (U.S. Patent No. 11389526). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11389526

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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