The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Nov. 08, 2019
Applicants:

Gachon University of Industry-academic Cooperation Foundation, Gyeonggi-do, KR;

Gil Medical Center, Incheon, KR;

Inventors:

Mee Sup Yoon, Incheon, KR;

Jie Chen, Urbana, IL (US);

Kook Son, Busan, KR;

Cheol Soo Choi, Incheon, KR;

Sunghoon Kim, Seoul, KR;

Jung Min Han, Gwangju, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/53 (2006.01); A61P 21/06 (2006.01); C12N 9/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 38/53 (2013.01); A61P 21/06 (2018.01); C12N 9/93 (2013.01); C12Y 601/01004 (2013.01); G01N 33/5023 (2013.01);
Abstract

The present invention relates to a composition comprising the UNE-L domain of leucyl-tRNA synthetase as an effective ingredient for increasing muscle. More particularly, the UNE-L domain of LRS according to the present invention, which is a region that controls activity of Vps34, activates mTORC1 involved in protein synthesis and increases myocyte differentiation and muscle fiber regeneration, thus finding useful application in muscle augmentation.


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