The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Apr. 06, 2021
Applicant:

University of Maryland, Baltimore, Baltimore, MD (US);

Inventors:

Jacques Ravel, Laurel, MD (US);

Michael France, Baltimore, MD (US);

Lindsay Rutt, Baltimore, MD (US);

Bing Ma, Baltimore, MD (US);

Assignee:

University of Maryland, Baltimore, Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/742 (2015.01); A01N 63/00 (2020.01); A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 35/74 (2015.01);
U.S. Cl.
CPC ...
A61K 35/742 (2013.01); A61K 35/74 (2013.01);
Abstract

Methods of formulating live biotherapeutics are disclosed in which a deficiency or excess of a specific bacterial strain in a person's microbiome is identified by comparing a gene-specific characterization of the person's microbiome against a comprehensive, non-redundant reference gene catalog, and the biotherapeutic is formulated by selecting bacteria to address the deficiency or excess. Embodiments include the formulation of live biotherapeutics for improving the health of a person's vaginal microbiome, i.e. using a vaginal reference gene catalog, and may be suitable for ameliorating, treating, or preventing a malignancy such as a cancer of the female genitourinary system.


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