The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Sep. 06, 2019
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Jonathan L. Sessler, Austin, TX (US);
Jonathan Arambula, Austin, TX (US);
Zahid H. Siddik, Houston, TX (US);
Gregory Thiabaud, Austin, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); A61K 31/407 (2006.01); A61K 31/4188 (2006.01); C07D 487/22 (2006.01); C07D 405/14 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 49/08 (2006.01); A61K 49/10 (2006.01); C07F 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/555 (2013.01); A61K 47/546 (2017.08); A61K 47/547 (2017.08); A61K 47/60 (2017.08); A61K 49/085 (2013.01); A61K 49/10 (2013.01); A61K 49/106 (2013.01); C07D 487/22 (2013.01); C07F 15/0093 (2013.01);
Abstract
The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.